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Deciphering the Code for Retroviral Integration Target Site Selection

Upon cell invasion, retroviruses generate a DNA copy of their RNA genome and integrate retroviral cDNA within host chromosomal DNA. Integration occurs throughout the host cell genome, but target site selection is not random. Each subgroup of retrovirus is distinguished from the others by attraction...

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Detalles Bibliográficos
Autores principales: Santoni, Federico Andrea, Hartley, Oliver, Luban, Jeremy
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2991247/
https://www.ncbi.nlm.nih.gov/pubmed/21124862
http://dx.doi.org/10.1371/journal.pcbi.1001008