The Subtilisin-Like Protease AprV2 Is Required for Virulence and Uses a Novel Disulphide-Tethered Exosite to Bind Substrates

Many bacterial pathogens produce extracellular proteases that degrade the extracellular matrix of the host and therefore are involved in disease pathogenesis. Dichelobacter nodosus is the causative agent of ovine footrot, a highly contagious disease that is characterized by the separation of the hoo...

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Detalles Bibliográficos
Autores principales: Kennan, Ruth M., Wong, Wilson, Dhungyel, Om P., Han, Xiaoyan, Wong, David, Parker, Dane, Rosado, Carlos J., Law, Ruby H. P., McGowan, Sheena, Reeve, Shane B., Levina, Vita, Powers, Glenn A., Pike, Robert N., Bottomley, Stephen P., Smith, A. Ian, Marsh, Ian, Whittington, Richard J., Whisstock, James C., Porter, Corrine J., Rood, Julian I.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2991261/
https://www.ncbi.nlm.nih.gov/pubmed/21124876
http://dx.doi.org/10.1371/journal.ppat.1001210

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