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Essential Functions of the Histone Demethylase Lid

Drosophila Little imaginal discs (Lid) is a recently described member of the JmjC domain class of histone demethylases that specifically targets trimethylated histone H3 lysine 4 (H3K4me3). To understand its biological function, we have utilized a series of Lid deletions and point mutations to asses...

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Detalles Bibliográficos
Autores principales: Li, Ling, Greer, Christina, Eisenman, Robert N., Secombe, Julie
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2991268/
https://www.ncbi.nlm.nih.gov/pubmed/21124823
http://dx.doi.org/10.1371/journal.pgen.1001221