A Molecular Mechanism for Eflornithine Resistance in African Trypanosomes

Human African trypanosomiasis, endemic to sub-Saharan Africa, is invariably fatal if untreated. Its causative agent is the protozoan parasite Trypanosoma brucei. Eflornithine is used as a first line treatment for human African trypanosomiasis, but there is a risk that resistance could thwart its use...

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Detalles Bibliográficos
Autores principales: Vincent, Isabel M., Creek, Darren, Watson, David G., Kamleh, Mohammed A., Woods, Debra J., Wong, Pui Ee, Burchmore, Richard J. S., Barrett, Michael P.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2991269/
https://www.ncbi.nlm.nih.gov/pubmed/21124824
http://dx.doi.org/10.1371/journal.ppat.1001204

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