Cargando…

Improved prognostic classification of breast cancer defined by antagonistic activation patterns of immune response pathway modules

BACKGROUND: Elucidating the activation pattern of molecular pathways across a given tumour type is a key challenge necessary for understanding the heterogeneity in clinical response and for developing novel more effective therapies. Gene expression signatures of molecular pathway activation derived...

Descripción completa

Detalles Bibliográficos
Autores principales:	Teschendorff, Andrew E, Gomez, Sergio, Arenas, Alex, El-Ashry, Dorraya, Schmidt, Marcus, Gehrmann, Mathias, Caldas, Carlos
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2991308/ https://www.ncbi.nlm.nih.gov/pubmed/21050467 http://dx.doi.org/10.1186/1471-2407-10-604

Ejemplares similares

Prognostic gene network modules in breast cancer hold promise
por: Teschendorff, Andrew E, et al.
Publicado: (2010)

Liquid biopsy: expanding the frontier of circulating biomarker discovery and validation in breast cancer
por: Miller, Philip C., et al.
Publicado: (2019)

Hyaluronan, Cancer-Associated Fibroblasts and the Tumor Microenvironment in Malignant Progression
por: McCarthy, James B., et al.
Publicado: (2018)

Corrigendum: Hyaluronan, Cancer-Associated Fibroblasts and the Tumor Microenvironment in Malignant Progression
por: McCarthy, James B., et al.
Publicado: (2018)

Suppression of Tumor Growth, Metastasis, and Signaling Pathways by Reducing FOXM1 Activity in Triple Negative Breast Cancer
por: Dey, Parama, et al.
Publicado: (2020)

Comparison of scores for bimodality of gene expression distributions and genome-wide evaluation of the prognostic relevance of high-scoring genes
por: Hellwig, Birte, et al.
Publicado: (2010)

A New Mouse Model for the Study of Human Breast Cancer Metastasis
por: Iorns, Elizabeth, et al.
Publicado: (2012)

Applying antagonistic activation pattern to the single-trial classification of mental arithmetic
por: Liu, Shixian
Publicado: (2022)

Stochastic epigenetic outliers can define field defects in cancer
por: Teschendorff, Andrew E., et al.
Publicado: (2016)

Immunoglobulin kappa chain as an immunologic biomarker of prognosis and chemotherapy response in solid tumors
por: Schmidt, Marcus, et al.
Publicado: (2012)

A robust classifier of high predictive value to identify good prognosis patients in ER-negative breast cancer
por: Teschendorff, Andrew E, et al.
Publicado: (2008)

The breast cancer somatic 'muta-ome': tackling the complexity
por: Teschendorff, Andrew E, et al.
Publicado: (2009)

An immune response gene expression module identifies a good prognosis subtype in estrogen receptor negative breast cancer
por: Teschendorff, Andrew E, et al.
Publicado: (2007)

Prevalence and prognostic value of cirrhotic cardiomyopathy as defined according to the proposed new classification
por: Cesari, Maurizio, et al.
Publicado: (2021)

Clinicopathological features and prognostic outcomes of molecularly defined entities in the new edition of the WHO classification of sinonasal carcinoma
por: Vuong, Huy Gia, et al.
Publicado: (2023)

Defining Epiglottic Collapses Patterns in Obstructive Sleep Apnea Patients: Francia-Lugo Classification
por: Francia, Carlos, et al.
Publicado: (2023)

A consensus prognostic gene expression classifier for ER positive breast cancer
por: Teschendorff, Andrew E, et al.
Publicado: (2006)

Validation of the molecular international prognostic scoring system in patients with myelodysplastic syndromes defined by international consensus classification
por: Lee, Wan-Hsuan, et al.
Publicado: (2023)

Defining plant ecological specialists and generalists: Building a framework for identification and classification
por: Kirsch, Alex, et al.
Publicado: (2022)

Prognostic Impact of LAG-3 mRNA Expression in Early Breast Cancer
por: Heimes, Anne-Sophie, et al.
Publicado: (2022)

Prognostic Significance of Interferon-γ and Its Signaling Pathway in Early Breast Cancer Depends on the Molecular Subtypes
por: Heimes, Anne-Sophie, et al.
Publicado: (2020)

A comparison of feature selection and classification methods in DNA methylation studies using the Illumina Infinium platform
por: Zhuang, Joanna, et al.
Publicado: (2012)

Intra-Tumour Signalling Entropy Determines Clinical Outcome in Breast and Lung Cancer
por: Banerji, Christopher R. S., et al.
Publicado: (2015)

Molecular and Serological Diagnostic Approach to Define the Microbiological Origin of Blood Culture-Negative Infective Endocarditis
por: El-Ashry, Amira H., et al.
Publicado: (2022)

A comprehensive analysis of prognostic signatures reveals the high predictive capacity of the Proliferation, Immune response and RNA splicing modules in breast cancer
por: Reyal, Fabien, et al.
Publicado: (2008)

The antagonistic modulation of Arp2/3 activity by N-WASP, WAVE2 and PICK1 defines dynamic changes in astrocyte morphology
por: Murk, Kai, et al.
Publicado: (2013)

Prognostic Impact of Immunoglobulin Kappa C (IGKC) in Early Breast Cancer
por: Schmidt, Marcus, et al.
Publicado: (2021)

Formalization of the classification pattern: survey of classification modeling in information systems engineering
por: Partridge, Chris, et al.
Publicado: (2016)

Molecular Classification of Endometrial Stromal Sarcomas Using RNA Sequencing Defines Nosological and Prognostic Subgroups with Different Natural History
por: Brahmi, Mehdi, et al.
Publicado: (2020)

P721: VALIDATION OF THE MOLECULAR INTERNATIONAL PROGNOSTIC SCORING SYSTEM IN PATIENTS WITH MYELODYSPLASTIC SYNDROMES DEFINED BY INTERNATIONAL CONSENSUS CLASSIFICATION
por: Hsuan Lee, Wan, et al.
Publicado: (2023)

Elucidating the Altered Transcriptional Programs in Breast Cancer using Independent Component Analysis
por: Teschendorff, Andrew E, et al.
Publicado: (2007)

Defining quality classification categories for complex system products
por: Hameri, A P
Publicado: (1999)

Defining the dance: quantification and classification of endoplasmic reticulum dynamics
por: Pain, Charlotte, et al.
Publicado: (2020)

Triple negative breast cancer initiating cell subsets differ in functional and molecular characteristics and in γ-secretase inhibitor drug responses
por: Azzam, Diana J, et al.
Publicado: (2013)

Effective approach to epidemic containment using link equations in complex networks
por: Matamalas, Joan T., et al.
Publicado: (2018)

Influence of trust in the spreading of information
por: Wu, Hongrun, et al.
Publicado: (2017)

A link model approach to identify congestion hotspots
por: Bassolas, Aleix, et al.
Publicado: (2022)

Intracellular patterns of sialophorin expression define a new molecular classification of breast cancer and represent new targets for therapy
por: Fu, Q, et al.
Publicado: (2014)

PCR-Based Simple Subgrouping Is Validated for Classification of Gliomas and Defines Negative Prognostic Copy Number Aberrations in IDH Mutant Gliomas
por: Nakae, Shunsuke, et al.
Publicado: (2015)

Towards Dendrite Spherical Neurons for Pattern Classification
por: Gómez-Flores, Wilfrido, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_1of4lf890o2475uoe8fo5edmce