JULIDE: A Software Tool for 3D Reconstruction and Statistical Analysis of Autoradiographic Mouse Brain Sections

In this article we introduce JULIDE, a software toolkit developed to perform the 3D reconstruction, intensity normalization, volume standardization by 3D image registration and voxel-wise statistical analysis of autoradiographs of mouse brain sections. This software tool has been developed in the op...

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Detalles Bibliográficos
Autores principales: Ribes, Delphine, Parafita, Julia, Charrier, Rémi, Magara, Fulvio, Magistretti, Pierre J., Thiran, Jean-Philippe
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2991313/
https://www.ncbi.nlm.nih.gov/pubmed/21124830
http://dx.doi.org/10.1371/journal.pone.0014094
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author Ribes, Delphine
Parafita, Julia
Charrier, Rémi
Magara, Fulvio
Magistretti, Pierre J.
Thiran, Jean-Philippe
author_facet Ribes, Delphine
Parafita, Julia
Charrier, Rémi
Magara, Fulvio
Magistretti, Pierre J.
Thiran, Jean-Philippe
author_sort Ribes, Delphine
collection PubMed
description In this article we introduce JULIDE, a software toolkit developed to perform the 3D reconstruction, intensity normalization, volume standardization by 3D image registration and voxel-wise statistical analysis of autoradiographs of mouse brain sections. This software tool has been developed in the open-source ITK software framework and is freely available under a GPL license. The article presents the complete image processing chain from raw data acquisition to 3D statistical group analysis. Results of the group comparison in the context of a study on spatial learning are shown as an illustration of the data that can be obtained with this tool.
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spelling pubmed-29913132010-12-01 JULIDE: A Software Tool for 3D Reconstruction and Statistical Analysis of Autoradiographic Mouse Brain Sections Ribes, Delphine Parafita, Julia Charrier, Rémi Magara, Fulvio Magistretti, Pierre J. Thiran, Jean-Philippe PLoS One Research Article In this article we introduce JULIDE, a software toolkit developed to perform the 3D reconstruction, intensity normalization, volume standardization by 3D image registration and voxel-wise statistical analysis of autoradiographs of mouse brain sections. This software tool has been developed in the open-source ITK software framework and is freely available under a GPL license. The article presents the complete image processing chain from raw data acquisition to 3D statistical group analysis. Results of the group comparison in the context of a study on spatial learning are shown as an illustration of the data that can be obtained with this tool. Public Library of Science 2010-11-23 /pmc/articles/PMC2991313/ /pubmed/21124830 http://dx.doi.org/10.1371/journal.pone.0014094 Text en Ribes et al. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.
spellingShingle Research Article
Ribes, Delphine
Parafita, Julia
Charrier, Rémi
Magara, Fulvio
Magistretti, Pierre J.
Thiran, Jean-Philippe
JULIDE: A Software Tool for 3D Reconstruction and Statistical Analysis of Autoradiographic Mouse Brain Sections
title JULIDE: A Software Tool for 3D Reconstruction and Statistical Analysis of Autoradiographic Mouse Brain Sections
title_full JULIDE: A Software Tool for 3D Reconstruction and Statistical Analysis of Autoradiographic Mouse Brain Sections
title_fullStr JULIDE: A Software Tool for 3D Reconstruction and Statistical Analysis of Autoradiographic Mouse Brain Sections
title_full_unstemmed JULIDE: A Software Tool for 3D Reconstruction and Statistical Analysis of Autoradiographic Mouse Brain Sections
title_short JULIDE: A Software Tool for 3D Reconstruction and Statistical Analysis of Autoradiographic Mouse Brain Sections
title_sort julide: a software tool for 3d reconstruction and statistical analysis of autoradiographic mouse brain sections
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2991313/
https://www.ncbi.nlm.nih.gov/pubmed/21124830
http://dx.doi.org/10.1371/journal.pone.0014094
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