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Cucurbitacin I Inhibits Cell Motility by Indirectly Interfering with Actin Dynamics

BACKGROUND: Cucurbitacins are plant natural products that inhibit activation of the Janus kinase 2 (JAK2)/signal transducer and activator of transcription 3 (STAT3) pathway by an unknown mechanism. They are also known to cause changes in the organization of the actin cytoskeleton. METHODOLOGY/PRINCI...

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Detalles Bibliográficos
Autores principales:	Knecht, David A., LaFleur, Rebecca A., Kahsai, Alem W., Argueta, Christian E., Beshir, Anwar B., Fenteany, Gabriel
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2991314/ https://www.ncbi.nlm.nih.gov/pubmed/21124831 http://dx.doi.org/10.1371/journal.pone.0014039

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