Mitochondrial Rejuvenation After Induced Pluripotency

BACKGROUND: As stem cells of the early embryo mature and differentiate into all tissues, the mitochondrial complement undergoes dramatic functional improvement. Mitochondrial activity is low to minimize generation of DNA-damaging reactive oxygen species during pre-implantation development and increa...

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Detalles Bibliográficos
Autores principales: Suhr, Steven T., Chang, Eun Ah, Tjong, Jonathan, Alcasid, Nathan, Perkins, Guy A., Goissis, Marcelo D., Ellisman, Mark H., Perez, Gloria I., Cibelli, Jose B.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2991355/
https://www.ncbi.nlm.nih.gov/pubmed/21124794
http://dx.doi.org/10.1371/journal.pone.0014095

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