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Thyroid Stimulating Hormone Receptor (TSHR) Intron 1 Variants Are Major Risk Factors for Graves' Disease in Three European Caucasian Cohorts

BACKGROUND: The thyroid stimulating hormone receptor (TSHR) gene is an established susceptibility locus for Graves' disease (GD), with recent studies refining association to two single nucleotide polymorphisms (SNPs), rs179247 and rs12101255, within TSHR intron 1. METHODOLOGY AND PRINCIPAL FIND...

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Detalles Bibliográficos
Autores principales:	Płoski, Rafał, Brand, Oliver J., Jurecka-Lubieniecka, Beata, Franaszczyk, Maria, Kula, Dorota, Krajewski, Paweł, Karamat, Muhammad A., Simmonds, Matthew J., Franklyn, Jayne A., Gough, Stephen C. L., Jarząb, Barbara, Bednarczuk, Tomasz
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2991361/ https://www.ncbi.nlm.nih.gov/pubmed/21124799 http://dx.doi.org/10.1371/journal.pone.0015512

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