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Notch and MAML-1 Complexation Do Not Detectably Alter the DNA Binding Specificity of the Transcription Factor CSL

BACKGROUND: Canonical Notch signaling is initiated when ligand binding induces proteolytic release of the intracellular part of Notch (ICN) from the cell membrane. ICN then travels into the nucleus where it drives the assembly of a transcriptional activation complex containing the DNA-binding transc...

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Detalles Bibliográficos
Autores principales:	Del Bianco, Cristina, Vedenko, Anastasia, Choi, Sung Hee, Berger, Michael F., Shokri, Leila, Bulyk, Martha L., Blacklow, Stephen C.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2991368/ https://www.ncbi.nlm.nih.gov/pubmed/21124806 http://dx.doi.org/10.1371/journal.pone.0015034

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