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Crystal Structure of Human Interferon-λ1 in Complex with Its High-Affinity Receptor Interferon-λR1

Interferon (IFN)-λ1 [also known as interleukin (IL)-29] belongs to the recently discovered group of type III IFNs. All type III IFNs initiate signaling processes through formation of specific heterodimeric receptor complexes consisting of IFN-λR1 and IL-10R2. We have determined the structure of huma...

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Detalles Bibliográficos
Autores principales: Miknis, Zachary J., Magracheva, Eugenia, Li, Wei, Zdanov, Alexander, Kotenko, Sergei V., Wlodawer, Alexander
Formato: Texto
Lenguaje:English
Publicado: Elsevier 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2991516/
https://www.ncbi.nlm.nih.gov/pubmed/20934432
http://dx.doi.org/10.1016/j.jmb.2010.09.068