Cargando…

Crystal Structure of Human Interferon-λ1 in Complex with Its High-Affinity Receptor Interferon-λR1

Interferon (IFN)-λ1 [also known as interleukin (IL)-29] belongs to the recently discovered group of type III IFNs. All type III IFNs initiate signaling processes through formation of specific heterodimeric receptor complexes consisting of IFN-λR1 and IL-10R2. We have determined the structure of huma...

Descripción completa

Detalles Bibliográficos
Autores principales:	Miknis, Zachary J., Magracheva, Eugenia, Li, Wei, Zdanov, Alexander, Kotenko, Sergei V., Wlodawer, Alexander
Formato:	Texto
Lenguaje:	English
Publicado:	Elsevier 2010
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2991516/ https://www.ncbi.nlm.nih.gov/pubmed/20934432 http://dx.doi.org/10.1016/j.jmb.2010.09.068

Ejemplares similares

A model of the ternary complex of interleukin-10 with its soluble receptors
por: Pletnev, Sergei, et al.
Publicado: (2005)

Interferon-λ at the Center of the Storm
por: Hendricks, Matthew R., et al.
Publicado: (2020)

Interferon-λ in HCV Infection and Therapy
por: Pagliaccetti, Nicole E., et al.
Publicado: (2010)

The Unresolved Role of Interferon-λ in Asthma Bronchiale
por: Sopel, Nina, et al.
Publicado: (2017)

Interferon-λ3/4 genetic variants and interferon-λ3 serum levels are biomarkers of lupus nephritis and disease activity in Taiwanese
por: Chen, Ji-Yih, et al.
Publicado: (2018)

STAT1 is essential for the inhibition of hepatitis C virus replication by interferon-λ but not by interferon-α
por: Yamauchi, Shota, et al.
Publicado: (2016)

Interferon-λ: Immune Functions at Barrier Surfaces and Beyond
por: Lazear, Helen M., et al.
Publicado: (2015)

Editorial: Interferon-λs: New Regulators of Inflammatory Processes
por: Zanoni, Ivan, et al.
Publicado: (2019)

Regulation and Function of Interferon-Lambda (IFNλ) and Its Receptor in Asthma
por: Krammer, Susanne, et al.
Publicado: (2021)

Interferon-λ Genetic Variations and Hepatitis C: Yet to be Discovered
por: Keshvari, Maryam, et al.
Publicado: (2014)

Interferon (IFN)-λ is a potential mediator in lupus nephritis
por: Zickert, Agneta, et al.
Publicado: (2016)

Interferon-λs and Plasmacytoid Dendritic Cells: A Close Relationship
por: Finotti, Giulia, et al.
Publicado: (2017)

Porcine deltacoronavirus (PDCoV) infection antagonizes interferon-λ1 production
por: Liu, Shudan, et al.
Publicado: (2020)

Interferon-λ and interleukin-22 cooperate for the induction of interferon-stimulated genes and control of rotavirus infection
por: Hernández, Pedro P., et al.
Publicado: (2015)

Clean and folded: Production of active, high quality recombinant human interferon-λ1
por: Shaldzhyan, Aram, et al.
Publicado: (2021)

Interferon-λs: Front-Line Guardians of Immunity and Homeostasis in the Respiratory Tract
por: Andreakos, Evangelos, et al.
Publicado: (2017)

Interferon-λ in the Context of Viral Infections: Production, Response and Therapeutic Implications
por: Hermant, Pascale, et al.
Publicado: (2014)

Interferon-λ Attenuates Rabies Virus Infection by Inducing Interferon-Stimulated Genes and Alleviating Neurological Inflammation
por: Li, Yingying, et al.
Publicado: (2020)

IFN‐λ4 inhibits HIV infection of macrophages through signalling of IFN‐λR1/IL‐10R2 receptor complex
por: Su, Qi‐Jian, et al.
Publicado: (2018)

Interferon (IFN)-λ Takes the Helm: Immunomodulatory Roles of Type III IFNs
por: Zanoni, Ivan, et al.
Publicado: (2017)

May interferon λ be a novel therapeutic approach against COVID-19?
por: Roohi, Azam, et al.
Publicado: (2021)

The Role of Interferon-λ Locus Polymorphisms in Hepatitis C and Other Infectious Diseases
por: Griffiths, Samantha J., et al.
Publicado: (2015)

Effect of human interferon-λ1 recombinant adenovirus on a gastric cancer orthotopic transplantation model
por: BU, XU-FENG, et al.
Publicado: (2014)

Dendritic cells-derived interferon-λ1 ameliorated inflammatory bone destruction through inhibiting osteoclastogenesis
por: Chen, Yueqi, et al.
Publicado: (2020)

Interferon-λ(4) (IFNL4) Transcript Expression in Human Liver Tissue Samples
por: Amanzada, Ahmad, et al.
Publicado: (2013)

Genetic variants in interferon-λ 4 influences HCV clearance in Chinese Han population
por: Huang, Peng, et al.
Publicado: (2017)

ID: 101: Investigating the role of interferon λ4 in hepatitis C virus infection
por: Terczynska-Dyla, Ewa, et al.
Publicado: (2015)

Cyclophilin inhibitors restrict Middle East respiratory syndrome coronavirus via interferon-λ in vitro and in mice
por: Sauerhering, Lucie, et al.
Publicado: (2020)

Species Specificity of Type III Interferon Activity and Development of a Sensitive Luciferase-Based Bioassay for Quantitation of Mouse Interferon-λ
por: Jacobs, Sophie, et al.
Publicado: (2018)

Interferon lambda 4 signals via the IFNλ receptor to regulate antiviral activity against HCV and coronaviruses
por: Hamming, Ole J, et al.
Publicado: (2013)

Targeted Induction of Interferon-λ in Humanized Chimeric Mouse Liver Abrogates Hepatotropic Virus Infection
por: Nakagawa, Shin-ichiro, et al.
Publicado: (2013)

Circulating Interferon-λ3, Responsiveness to HBV Vaccination, and HBV/HCV Infections in Haemodialysis Patients
por: Grzegorzewska, Alicja E., et al.
Publicado: (2017)

Identification of a Predominantly Interferon-λ-Induced Transcriptional Profile in Murine Intestinal Epithelial Cells
por: Selvakumar, Tharini A., et al.
Publicado: (2017)

Interferon-λ3 Promotes Epithelial Defense and Barrier Function Against Cryptosporidium parvum Infection
por: Ferguson, Sylvia H., et al.
Publicado: (2019)

Nasal commensal Staphylococcus epidermidis enhances interferon-λ-dependent immunity against influenza virus
por: Kim, Hyun Jik, et al.
Publicado: (2019)

Interferon-λ3 rs12979860 can regulate inflammatory cytokines production in pulmonary fibrosis
por: Hamdi, Eman, et al.
Publicado: (2023)

1346. Genetic Variation at the Interferon λ Locus and Association with Clinical Outcome and Severity of COVID-19
por: Alalwan, Dana, et al.
Publicado: (2023)

Respiratory virus–induced EGFR activation suppresses IRF1-dependent interferon λ and antiviral defense in airway epithelium
por: Ueki, Iris F., et al.
Publicado: (2013)

The μ2 and λ1 Proteins of Mammalian Reovirus Modulate Early Events Leading to Induction of the Interferon Signaling Network
por: Després, Guillaume David, et al.
Publicado: (2022)

Tables of λ , k°, ∑± lifetimes and λ°, k° decay branching ratios
por: Glaser, D A, et al.
Publicado: (1958)

Cannot write session to /tmp/vufind_sessions/sess_1viurbnf4na4n5ia5jpncfn39d