Peroxisome Proliferator-Activated Receptor -β/δ, -γ Agonists and Resveratrol Modulate Hypoxia Induced Changes in Nuclear Receptor Activators of Muscle Oxidative Metabolism

PPAR-α, PPAR-β, and PPAR-γ, and RXR in conjunction with PGC-1α and SIRT1, activate oxidative metabolism genes determining insulin sensitivity. In utero, hypoxia is commonly observed in Intrauterine Growth Restriction (IUGR), and reduced insulin sensitivity is often observed in these infants as adult...

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Detalles Bibliográficos
Autores principales: Regnault, Timothy R. H., Zhao, Lin, Chiu, Jacky S. S., Gottheil, Stephanie K., Foran, Allison, Yee, Siu-Pok
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2991640/
https://www.ncbi.nlm.nih.gov/pubmed/21113404
http://dx.doi.org/10.1155/2010/129173

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