EFFECT OF IMIPRAMINE AND ECT ON PLATELET MAO ACTIVITY IN DEPRESSIVES

Platelet monoamine Oxidase (MAO) activity was estimated in 30 depressed patients treated with Imipramine or EGT over a period of 5 weeks and pretreatment and post treatment values were compared. Imipramine and ECT caused significant reduction of platelet MAO, which after 7 days washout period comes...

Descripción completa

Detalles Bibliográficos
Autores principales: Trivedi, J.K., Singh, R.P., Lal, Narottam, Viswanathan, P.N., Kumar, Sudhir
Formato: Texto
Lenguaje:English
Publicado: Medknow Publications 1989
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2991675/
https://www.ncbi.nlm.nih.gov/pubmed/21927372
_version_ 1782192621852033024
author Trivedi, J.K.
Singh, R.P.
Lal, Narottam
Viswanathan, P.N.
Kumar, Sudhir
author_facet Trivedi, J.K.
Singh, R.P.
Lal, Narottam
Viswanathan, P.N.
Kumar, Sudhir
author_sort Trivedi, J.K.
collection PubMed
description Platelet monoamine Oxidase (MAO) activity was estimated in 30 depressed patients treated with Imipramine or EGT over a period of 5 weeks and pretreatment and post treatment values were compared. Imipramine and ECT caused significant reduction of platelet MAO, which after 7 days washout period comes to the pretreatment level while subjects clinical status l remained unchanged. The percentage blockade in platelet MAO values by Imipramine and ECT was 51.40±13.43 and 34.73±24.27 respectively.
format Text
id pubmed-2991675
institution National Center for Biotechnology Information
language English
publishDate 1989
publisher Medknow Publications
record_format MEDLINE/PubMed
spelling pubmed-29916752011-09-16 EFFECT OF IMIPRAMINE AND ECT ON PLATELET MAO ACTIVITY IN DEPRESSIVES Trivedi, J.K. Singh, R.P. Lal, Narottam Viswanathan, P.N. Kumar, Sudhir Indian J Psychiatry Original Article Platelet monoamine Oxidase (MAO) activity was estimated in 30 depressed patients treated with Imipramine or EGT over a period of 5 weeks and pretreatment and post treatment values were compared. Imipramine and ECT caused significant reduction of platelet MAO, which after 7 days washout period comes to the pretreatment level while subjects clinical status l remained unchanged. The percentage blockade in platelet MAO values by Imipramine and ECT was 51.40±13.43 and 34.73±24.27 respectively. Medknow Publications 1989 /pmc/articles/PMC2991675/ /pubmed/21927372 Text en Copyright: © Indian Journal of Psychiatry http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Trivedi, J.K.
Singh, R.P.
Lal, Narottam
Viswanathan, P.N.
Kumar, Sudhir
EFFECT OF IMIPRAMINE AND ECT ON PLATELET MAO ACTIVITY IN DEPRESSIVES
title EFFECT OF IMIPRAMINE AND ECT ON PLATELET MAO ACTIVITY IN DEPRESSIVES
title_full EFFECT OF IMIPRAMINE AND ECT ON PLATELET MAO ACTIVITY IN DEPRESSIVES
title_fullStr EFFECT OF IMIPRAMINE AND ECT ON PLATELET MAO ACTIVITY IN DEPRESSIVES
title_full_unstemmed EFFECT OF IMIPRAMINE AND ECT ON PLATELET MAO ACTIVITY IN DEPRESSIVES
title_short EFFECT OF IMIPRAMINE AND ECT ON PLATELET MAO ACTIVITY IN DEPRESSIVES
title_sort effect of imipramine and ect on platelet mao activity in depressives
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2991675/
https://www.ncbi.nlm.nih.gov/pubmed/21927372
work_keys_str_mv AT trivedijk effectofimipramineandectonplateletmaoactivityindepressives
AT singhrp effectofimipramineandectonplateletmaoactivityindepressives
AT lalnarottam effectofimipramineandectonplateletmaoactivityindepressives
AT viswanathanpn effectofimipramineandectonplateletmaoactivityindepressives
AT kumarsudhir effectofimipramineandectonplateletmaoactivityindepressives

Ejemplares similares