Acute akathisia with quetiapine: A case report and review of literature

Quetiapine is an atypical antipsychotic which has been shown to have greater relative affinity for 5-HT(2A) receptors than for D(2) receptors, due to which it is thought to lead to lower incidence of extrapyramidal symptoms (EPS). However, over the years literature in the form of case reports have a...

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Detalles Bibliográficos
Autores principales: Shah, Ruchita, Grover, Sandeep, Maheshwari, Uma, Kate, Natasha, Malhotra, Nidhi
Formato: Texto
Lenguaje:English
Publicado: Medknow Publications 2010
Materias:
Drug Watch
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2991706/
https://www.ncbi.nlm.nih.gov/pubmed/21189919
http://dx.doi.org/10.4103/0253-7613.71896
Descripción
Sumario:Quetiapine is an atypical antipsychotic which has been shown to have greater relative affinity for 5-HT(2A) receptors than for D(2) receptors, due to which it is thought to lead to lower incidence of extrapyramidal symptoms (EPS). However, over the years literature in the form of case reports have accumulated which shows that quetiapine can lead to akathisia, especially in subjects prone to develop EPS. In this study, we report the case of a 22-year-old female who developed akathisia with quetiapine 150 mg/day, which subsided with reduction in dose. We have also reviewed the existing literature with respect to akathisia with quetiapine.

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