Acute akathisia with quetiapine: A case report and review of literature

Quetiapine is an atypical antipsychotic which has been shown to have greater relative affinity for 5-HT(2A) receptors than for D(2) receptors, due to which it is thought to lead to lower incidence of extrapyramidal symptoms (EPS). However, over the years literature in the form of case reports have a...

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Autores principales: Shah, Ruchita, Grover, Sandeep, Maheshwari, Uma, Kate, Natasha, Malhotra, Nidhi
Formato: Texto
Lenguaje:English
Publicado: Medknow Publications 2010
Materias:
Drug Watch
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2991706/
https://www.ncbi.nlm.nih.gov/pubmed/21189919
http://dx.doi.org/10.4103/0253-7613.71896
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author Shah, Ruchita
Grover, Sandeep
Maheshwari, Uma
Kate, Natasha
Malhotra, Nidhi
author_facet Shah, Ruchita
Grover, Sandeep
Maheshwari, Uma
Kate, Natasha
Malhotra, Nidhi
author_sort Shah, Ruchita
collection PubMed
description Quetiapine is an atypical antipsychotic which has been shown to have greater relative affinity for 5-HT(2A) receptors than for D(2) receptors, due to which it is thought to lead to lower incidence of extrapyramidal symptoms (EPS). However, over the years literature in the form of case reports have accumulated which shows that quetiapine can lead to akathisia, especially in subjects prone to develop EPS. In this study, we report the case of a 22-year-old female who developed akathisia with quetiapine 150 mg/day, which subsided with reduction in dose. We have also reviewed the existing literature with respect to akathisia with quetiapine.
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spelling pubmed-29917062010-12-28 Acute akathisia with quetiapine: A case report and review of literature Shah, Ruchita Grover, Sandeep Maheshwari, Uma Kate, Natasha Malhotra, Nidhi Indian J Pharmacol Drug Watch Quetiapine is an atypical antipsychotic which has been shown to have greater relative affinity for 5-HT(2A) receptors than for D(2) receptors, due to which it is thought to lead to lower incidence of extrapyramidal symptoms (EPS). However, over the years literature in the form of case reports have accumulated which shows that quetiapine can lead to akathisia, especially in subjects prone to develop EPS. In this study, we report the case of a 22-year-old female who developed akathisia with quetiapine 150 mg/day, which subsided with reduction in dose. We have also reviewed the existing literature with respect to akathisia with quetiapine. Medknow Publications 2010-12 /pmc/articles/PMC2991706/ /pubmed/21189919 http://dx.doi.org/10.4103/0253-7613.71896 Text en © Indian Journal of Pharmacology http://creativecommons.org/licenses/by/2.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Drug Watch
Shah, Ruchita
Grover, Sandeep
Maheshwari, Uma
Kate, Natasha
Malhotra, Nidhi
Acute akathisia with quetiapine: A case report and review of literature
title Acute akathisia with quetiapine: A case report and review of literature
title_full Acute akathisia with quetiapine: A case report and review of literature
title_fullStr Acute akathisia with quetiapine: A case report and review of literature
title_full_unstemmed Acute akathisia with quetiapine: A case report and review of literature
title_short Acute akathisia with quetiapine: A case report and review of literature
title_sort acute akathisia with quetiapine: a case report and review of literature
topic Drug Watch
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2991706/
https://www.ncbi.nlm.nih.gov/pubmed/21189919
http://dx.doi.org/10.4103/0253-7613.71896
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AT katenatasha acuteakathisiawithquetiapineacasereportandreviewofliterature
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