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Priorities for tuberculosis research: a systematic review

Reliable and relevant research can help to improve tuberculosis control worldwide. In recent years, various organisations have assessed research needs and proposed priorities for tuberculosis. We summarise existing priority statements and assess the rigour of the methods used to generate them. We fo...

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Autores principales: Rylance, Jamie, Pai, Madhukar, Lienhardt, Christian, Garner, Paul
Formato: Texto
Lenguaje:English
Publicado: Elsevier Science ;, The Lancet Pub. Group 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2992175/
https://www.ncbi.nlm.nih.gov/pubmed/21050822
http://dx.doi.org/10.1016/S1473-3099(10)70201-2
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author Rylance, Jamie
Pai, Madhukar
Lienhardt, Christian
Garner, Paul
author_facet Rylance, Jamie
Pai, Madhukar
Lienhardt, Christian
Garner, Paul
author_sort Rylance, Jamie
collection PubMed
description Reliable and relevant research can help to improve tuberculosis control worldwide. In recent years, various organisations have assessed research needs and proposed priorities for tuberculosis. We summarise existing priority statements and assess the rigour of the methods used to generate them. We found 33 documents that specifically outline priorities in tuberculosis research. The top priority areas were drug development (28 articles), diagnosis and diagnostic tests (27), epidemiology (20), health services research (16), basic research (13), and vaccine development and use (13). The most focused questions were on the treatment and prevention of multidrug-resistant tuberculosis in people co-infected with HIV. Methods used to identify these priorities were varied. Improvements can be made to ensure the process is more rigorous and transparent, and to use existing research or systematic reviews more often. WHO, Stop TB Partnership, and other organisations could adopt an incremental process of priority development, building on the existing knowledge base.
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spelling pubmed-29921752010-12-22 Priorities for tuberculosis research: a systematic review Rylance, Jamie Pai, Madhukar Lienhardt, Christian Garner, Paul Lancet Infect Dis Review Reliable and relevant research can help to improve tuberculosis control worldwide. In recent years, various organisations have assessed research needs and proposed priorities for tuberculosis. We summarise existing priority statements and assess the rigour of the methods used to generate them. We found 33 documents that specifically outline priorities in tuberculosis research. The top priority areas were drug development (28 articles), diagnosis and diagnostic tests (27), epidemiology (20), health services research (16), basic research (13), and vaccine development and use (13). The most focused questions were on the treatment and prevention of multidrug-resistant tuberculosis in people co-infected with HIV. Methods used to identify these priorities were varied. Improvements can be made to ensure the process is more rigorous and transparent, and to use existing research or systematic reviews more often. WHO, Stop TB Partnership, and other organisations could adopt an incremental process of priority development, building on the existing knowledge base. Elsevier Science ;, The Lancet Pub. Group 2010-12-10 /pmc/articles/PMC2992175/ /pubmed/21050822 http://dx.doi.org/10.1016/S1473-3099(10)70201-2 Text en © 2010 Elsevier Ltd. All rights reserved. https://creativecommons.org/licenses/by/4.0/This work is licensed under a Creative Commons Attribution 4.0 International License (https://creativecommons.org/licenses/by/4.0/) , which allows reusers to distribute, remix, adapt, and build upon the material in any medium or format, so long as attribution is given to the creator. The license allows for commercial use.
spellingShingle Review
Rylance, Jamie
Pai, Madhukar
Lienhardt, Christian
Garner, Paul
Priorities for tuberculosis research: a systematic review
title Priorities for tuberculosis research: a systematic review
title_full Priorities for tuberculosis research: a systematic review
title_fullStr Priorities for tuberculosis research: a systematic review
title_full_unstemmed Priorities for tuberculosis research: a systematic review
title_short Priorities for tuberculosis research: a systematic review
title_sort priorities for tuberculosis research: a systematic review
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2992175/
https://www.ncbi.nlm.nih.gov/pubmed/21050822
http://dx.doi.org/10.1016/S1473-3099(10)70201-2
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