Dose-Dependent Delay of the Hypoglycemic Effect of Short-Acting Insulin Analogs in Obese Subjects With Type 2 Diabetes: A pharmacokinetic and pharmacodynamic study

OBJECTIVE: Injected volume and subcutaneous adipose tissue blood flow (ATBF) affect insulin absorption. Pharmacokinetics of short-acting insulin analogs were established by assessing injection of small doses in lean subjects, healthy or with type 1 diabetes. In obese patients, however, daily dosages...

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Detalles Bibliográficos
Autores principales: Gagnon-Auger, Maude, du Souich, Patrick, Baillargeon, Jean-Patrice, Martin, Elisabeth, Brassard, Pascal, Ménard, Julie, Ardilouze, Jean-Luc
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2010
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2992178/
https://www.ncbi.nlm.nih.gov/pubmed/20841613
http://dx.doi.org/10.2337/dc10-1126

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