Cargando…
Menarchal Timing in Type 1 Diabetes Through the Last 4 Decades
OBJECTIVE: We sought to examine whether age at menarche has changed over the past 4 decades by comparing age at menarche by year of diagnosis with type 1 diabetes. RESEARCH DESIGN AND METHODS: This work consisted of a cross-sectional study of age at menarche in two cohorts: adolescents (ages 11–24 y...
Autores principales: | , , |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2010
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2992181/ https://www.ncbi.nlm.nih.gov/pubmed/20843975 http://dx.doi.org/10.2337/dc10-0872 |
_version_ | 1782192722541543424 |
---|---|
author | Schweiger, Bahareh Klingensmith, Georgeanna J. Snell-Bergeon, Janet K. |
author_facet | Schweiger, Bahareh Klingensmith, Georgeanna J. Snell-Bergeon, Janet K. |
author_sort | Schweiger, Bahareh |
collection | PubMed |
description | OBJECTIVE: We sought to examine whether age at menarche has changed over the past 4 decades by comparing age at menarche by year of diagnosis with type 1 diabetes. RESEARCH DESIGN AND METHODS: This work consisted of a cross-sectional study of age at menarche in two cohorts: adolescents (ages 11–24 years, n = 228) and adults (ages 19–55 years, n = 290, enrolled in the Coronary Artery Calcification in Type 1 Diabetes study). RESULTS: The adolescent cohort reported a younger age of menarche than the adult women with type 1 diabetes (12.69 ± 0.08 vs. 13.22 ± 0.12 years, mean ± SE, P < 0.001). Age at menarche was later in both adolescent girls and adult women with type 1 diabetes diagnosed before menarche (12.82 ± 1.16 and 13.7 ± 2.23 years) than for individuals diagnosed after menarche (12.12 ± 1.25 and 12.65 ± 1.38 years, P < 0.001 for both). Age at menarche was then examined by decade of type 1 diabetes diagnosis (1970–1979, 1980–1989, 1990–1999, and 2000–2009). Age at menarche significantly declined over the 4 decades (P = 0.0002). However, the delay in menarche among girls diagnosed with type 1 diabetes before menarche compared with those diagnosed after menarche was also significant across all decades (P < 0.0001) and did not change significantly over time (P = 0.41 for interaction of cohort and diagnosis premenarche). CONCLUSIONS: Age at menarche has declined over the past 4 decades among girls with type 1 diabetes, but a delay in age at menarche remains among individuals diagnosed before menarche compared with individuals diagnosed after menarche. |
format | Text |
id | pubmed-2992181 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2010 |
publisher | American Diabetes Association |
record_format | MEDLINE/PubMed |
spelling | pubmed-29921812011-12-01 Menarchal Timing in Type 1 Diabetes Through the Last 4 Decades Schweiger, Bahareh Klingensmith, Georgeanna J. Snell-Bergeon, Janet K. Diabetes Care Original Research OBJECTIVE: We sought to examine whether age at menarche has changed over the past 4 decades by comparing age at menarche by year of diagnosis with type 1 diabetes. RESEARCH DESIGN AND METHODS: This work consisted of a cross-sectional study of age at menarche in two cohorts: adolescents (ages 11–24 years, n = 228) and adults (ages 19–55 years, n = 290, enrolled in the Coronary Artery Calcification in Type 1 Diabetes study). RESULTS: The adolescent cohort reported a younger age of menarche than the adult women with type 1 diabetes (12.69 ± 0.08 vs. 13.22 ± 0.12 years, mean ± SE, P < 0.001). Age at menarche was later in both adolescent girls and adult women with type 1 diabetes diagnosed before menarche (12.82 ± 1.16 and 13.7 ± 2.23 years) than for individuals diagnosed after menarche (12.12 ± 1.25 and 12.65 ± 1.38 years, P < 0.001 for both). Age at menarche was then examined by decade of type 1 diabetes diagnosis (1970–1979, 1980–1989, 1990–1999, and 2000–2009). Age at menarche significantly declined over the 4 decades (P = 0.0002). However, the delay in menarche among girls diagnosed with type 1 diabetes before menarche compared with those diagnosed after menarche was also significant across all decades (P < 0.0001) and did not change significantly over time (P = 0.41 for interaction of cohort and diagnosis premenarche). CONCLUSIONS: Age at menarche has declined over the past 4 decades among girls with type 1 diabetes, but a delay in age at menarche remains among individuals diagnosed before menarche compared with individuals diagnosed after menarche. American Diabetes Association 2010-12 2010-09-15 /pmc/articles/PMC2992181/ /pubmed/20843975 http://dx.doi.org/10.2337/dc10-0872 Text en © 2010 by the American Diabetes Association. Readers may use this article as long as the work is properly cited, the use is educational and not for profit, and the work is not altered. See http://creativecommons.org/licenses/by-nc-nd/3.0/ for details. |
spellingShingle | Original Research Schweiger, Bahareh Klingensmith, Georgeanna J. Snell-Bergeon, Janet K. Menarchal Timing in Type 1 Diabetes Through the Last 4 Decades |
title | Menarchal Timing in Type 1 Diabetes Through the Last 4 Decades |
title_full | Menarchal Timing in Type 1 Diabetes Through the Last 4 Decades |
title_fullStr | Menarchal Timing in Type 1 Diabetes Through the Last 4 Decades |
title_full_unstemmed | Menarchal Timing in Type 1 Diabetes Through the Last 4 Decades |
title_short | Menarchal Timing in Type 1 Diabetes Through the Last 4 Decades |
title_sort | menarchal timing in type 1 diabetes through the last 4 decades |
topic | Original Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2992181/ https://www.ncbi.nlm.nih.gov/pubmed/20843975 http://dx.doi.org/10.2337/dc10-0872 |
work_keys_str_mv | AT schweigerbahareh menarchaltimingintype1diabetesthroughthelast4decades AT klingensmithgeorgeannaj menarchaltimingintype1diabetesthroughthelast4decades AT snellbergeonjanetk menarchaltimingintype1diabetesthroughthelast4decades |