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Analysis of the expression pattern of the BCL11B gene and its relatives in patients with T-cell acute lymphoblastic leukemia

BACKGROUND: In a human T-cell acute lymphoblastic leukemia (T-ALL) cell line (Molt-4), siRNA-mediated suppression of BCL11B expression was shown to inhibit proliferation and induce apoptosis, functions which may be related to genes involved in apoptosis (such as TNFSF10 and BCL2L1) and TGF-β pathway...

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Detalles Bibliográficos
Autores principales:	Huang, Xin, Chen, Shaohua, Shen, Qi, Yang, Lijian, Li, Bo, Zhong, Liye, Geng, Suxia, Du, Xin, Li, Yangqiu
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2992472/ https://www.ncbi.nlm.nih.gov/pubmed/21080944 http://dx.doi.org/10.1186/1756-8722-3-44

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