Cargando…

TFPI-2 is a putative tumor suppressor gene frequently inactivated by promoter hypermethylation in nasopharyngeal carcinoma

BACKGROUND: Epigenetic silencing of tumor suppressor genes play important roles in NPC tumorgenesis. Tissue factor pathway inhibitor-2 (TFPI-2), is a protease inhibitor. Recently, TFPI-2 was suggested to be a tumor suppressor gene involved in tumorigenesis and metastasis in some cancers. In this stu...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Shumin, Xiao, Xue, Zhou, Xiaoying, Huang, Tingting, Du, Chunping, Yu, Nana, Mo, Yingxi, Lin, Longde, Zhang, Jinyan, Ma, Ning, Murata, Mariko, Huang, Guangwu, Zhang, Zhe
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2992524/ https://www.ncbi.nlm.nih.gov/pubmed/21062455 http://dx.doi.org/10.1186/1471-2407-10-617

Ejemplares similares

Cytochrome b5 reductase 2 is a novel candidate tumor suppressor gene frequently inactivated by promoter hypermethylation in human nasopharyngeal carcinoma
por: Xiao, Xue, et al.
Publicado: (2013)

Epigenetic inactivation of follistatin-like 1 mediates tumor immune evasion in nasopharyngeal carcinoma
por: Zhou, Xiaoying, et al.
Publicado: (2016)

Putative tumour-suppressor gene DAB2 is frequently down regulated by promoter hypermethylation in nasopharyngeal carcinoma
por: Tong, Joanna H, et al.
Publicado: (2010)

The potent tumor suppressor miR-497 inhibits cancer phenotypes in nasopharyngeal carcinoma by targeting ANLN and HSPA4L
por: Wang, Shumin, et al.
Publicado: (2015)

The role of TFPI2 hypermethylation in the detection of gastric and colorectal cancer
por: Hu, Haochang, et al.
Publicado: (2017)

Epigenetic downregulation of the ISG15–conjugating enzyme UbcH8 impairs lipolysis and correlates with poor prognosis in nasopharyngeal carcinoma
por: Zhou, Xiaoying, et al.
Publicado: (2015)

Metallothionein III (MT3) is a putative tumor suppressor gene that is frequently inactivated in pediatric acute myeloid leukemia by promoter hypermethylation
por: Tao, Yan-Fang, et al.
Publicado: (2014)

Quantitation of DNA methylation in Epstein-Barr virus–associated nasopharyngeal carcinoma by bisulfite amplicon sequencing
por: Zhao, Weilin, et al.
Publicado: (2017)

Downregulation of SLC27A6 by DNA Hypermethylation Promotes Proliferation but Suppresses Metastasis of Nasopharyngeal Carcinoma Through Modulating Lipid Metabolism
por: Zhong, Xuemin, et al.
Publicado: (2022)

Inactivation of HMGCL promotes proliferation and metastasis of nasopharyngeal carcinoma by suppressing oxidative stress
por: Luo, Wenqi, et al.
Publicado: (2017)

RERG suppresses cell proliferation, migration and angiogenesis through ERK/NF-κB signaling pathway in nasopharyngeal carcinoma
por: Zhao, Weilin, et al.
Publicado: (2017)

Erratum to: RERG suppresses cell proliferation, migration and angiogenesis through ERK/NF-κB signaling pathway in nasopharyngeal carcinoma
por: Zhao, Weilin, et al.
Publicado: (2017)

Inactivation of 3-hydroxybutyrate dehydrogenase type 2 promotes proliferation and metastasis of nasopharyngeal carcinoma by iron retention
por: Li, Bo, et al.
Publicado: (2019)

Putative tumour suppressor gene necdin is hypermethylated and mutated in human cancer
por: De Faveri, L E, et al.
Publicado: (2013)

Epigenetic Inactivation of Acetyl-CoA Acetyltransferase 1 Promotes the Proliferation and Metastasis in Nasopharyngeal Carcinoma by Blocking Ketogenesis
por: Lu, Yunliang, et al.
Publicado: (2021)

Nasopharyngeal Epstein-Barr Virus Load: An Efficient Supplementary Method for Population-Based Nasopharyngeal Carcinoma Screening
por: Chen, Yufeng, et al.
Publicado: (2015)

Relationships of Alpha-SMA-Positive Fibroblasts and SDF-1-Positive Tumor Cells with Neoangiogenesis in Nasopharyngeal Carcinoma
por: Wang, Shumin, et al.
Publicado: (2014)

Frequent Promoter Hypermethylation of the APC and RASSF1A Tumour Suppressors in Parathyroid Tumours
por: Juhlin, C. Christofer, et al.
Publicado: (2010)

Inflammation-Related DNA Damage and Cancer Stem Cell Markers in Nasopharyngeal Carcinoma
por: Wang, Shumin, et al.
Publicado: (2016)

PCDH8 is Frequently Inactivated by Promoter Hypermethylation in Liver Cancer: Diagnostic and Clinical Significance
por: Zhang, Cheng, et al.
Publicado: (2016)

ZNF354C Mediated by DNMT1 Ameliorates Lung Ischemia-Reperfusion Oxidative Stress Injury by Reducing TFPI Promoter Methylation to Upregulate TFPI
por: Shi, Qi, et al.
Publicado: (2022)

ECRG4 is a candidate tumor suppressor gene frequently hypermethylated in colorectal carcinoma and glioma
por: Götze, Silke, et al.
Publicado: (2009)

ECRG4 acts as a tumor suppressor gene frequently hypermethylated in human breast cancer
por: Tang, Gao-Yan, et al.
Publicado: (2019)

Combination of RERG and ZNF671 methylation rates in circulating cell‐free DNA: A novel biomarker for screening of nasopharyngeal carcinoma
por: Xu, Yifei, et al.
Publicado: (2020)

Promoter Hypermethylation of KLF4 Inactivates Its Tumor Suppressor Function in Cervical Carcinogenesis
por: Yang, Wen-Ting, et al.
Publicado: (2014)

Protocadherin 17 is a tumor suppressor and is frequently methylated in nasopharyngeal carcinoma
por: He, Ya, et al.
Publicado: (2019)

Chick Chorioallantoic Membrane Assay: A 3D Animal Model for Study of Human Nasopharyngeal Carcinoma
por: Xiao, Xue, et al.
Publicado: (2015)

MBD3 promotes hepatocellular carcinoma progression and metastasis through negative regulation of tumour suppressor TFPI2
por: Yan, Weiwei, et al.
Publicado: (2022)

Tumor suppressor genes on frequently deleted chromosome 3p in nasopharyngeal carcinoma
por: Chen, Juan, et al.
Publicado: (2012)

Protocadherin 17 Is a Tumor Suppressor and Is Frequently Methylated in Nasopharyngeal Carcinoma [Retraction]
Publicado: (2020)

Reprimo, a Potential p53-Dependent Tumor Suppressor Gene, Is Frequently Hypermethylated in Estrogen Receptor α-Positive Breast Cancer
por: Buchegger, Kurt, et al.
Publicado: (2017)

TFPIα and TFPIβ are expressed at the surface of breast cancer cells and inhibit TF-FVIIa activity
por: Stavik, Benedicte, et al.
Publicado: (2013)

Inactivation of MSH3 by promoter methylation correlates with primary tumor stage in nasopharyngeal carcinoma
por: Ni, Haifeng, et al.
Publicado: (2017)

Hypermethylation of tumor suppressor lncRNA MEF2C-AS1 frequently happened in patients at all stages of colorectal carcinogenesis
por: Qian, Sangni, et al.
Publicado: (2022)

Inactivation of the tight junction gene CLDN11 by aberrant hypermethylation modulates tubulins polymerization and promotes cell migration in nasopharyngeal carcinoma
por: Li, Hsin-Pai, et al.
Publicado: (2018)

OPCML Is a Broad Tumor Suppressor for Multiple Carcinomas and Lymphomas with Frequently Epigenetic Inactivation
por: Cui, Yan, et al.
Publicado: (2008)

Promoter Hypermethylation of Tumor Suppressor Genes Located on Short Arm of the Chromosome 3 as Potential Biomarker for the Diagnosis of Nasopharyngeal Carcinoma
por: Lao, Thuan Duc, et al.
Publicado: (2021)

Caffeic acid phenethyl ester suppressed growth and metastasis of nasopharyngeal carcinoma cells by inactivating the NF-κB pathway
por: Liang, Yushan, et al.
Publicado: (2019)

Glutaredoxin 3 promotes nasopharyngeal carcinoma growth and metastasis via EGFR/Akt pathway and independent of ROS
por: He, Feng, et al.
Publicado: (2016)

Mechanisms of Anergic Inflammatory Response in Nasopharyngeal Carcinoma Cells Despite Ubiquitous Constitutive NF-κB Activation
por: Zhou, Xiaoying, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_ce6in8i51mip5nae8i415uu152