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NO signaling and S-nitrosylation regulate PTEN inhibition in neurodegeneration
BACKGROUND: The phosphatase PTEN governs the phosphoinositide 3-kinase (PI3K)/Akt signaling pathway which is arguably the most important pro-survival pathway in neurons. Recently, PTEN has also been implicated in multiple important CNS functions such as neuronal differentiation, plasticity, injury a...
| Autores principales: | , , , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2992530/ https://www.ncbi.nlm.nih.gov/pubmed/21067594 http://dx.doi.org/10.1186/1750-1326-5-49 |