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Disruption of Hepatic Leptin Signaling Protects Mice From Age- and Diet-Related Glucose Intolerance
OBJECTIVE: The liver plays a critical role in integrating and controlling glucose metabolism. Thus, it is important that the liver receive and react to signals from other tissues regarding the nutrient status of the body. Leptin, which is produced and secreted from adipose tissue, is a hormone that...
Autores principales: | Huynh, Frank K., Levi, Jasna, Denroche, Heather C., Gray, Sarah L., Voshol, Peter J., Neumann, Ursula H., Speck, Madeleine, Chua, Streamson C., Covey, Scott D., Kieffer, Timothy J. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2992763/ https://www.ncbi.nlm.nih.gov/pubmed/20876720 http://dx.doi.org/10.2337/db10-0074 |
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