Combined Neural Inactivation of Suppressor of Cytokine Signaling-3 and Protein-Tyrosine Phosphatase-1B Reveals Additive, Synergistic, and Factor-Specific Roles in the Regulation of Body Energy Balance

OBJECTIVE: The adipokine hormone leptin triggers signals in the brain that ultimately lead to decreased feeding and increased energy expenditure. However, obesity is most often associated with elevated plasma leptin levels and leptin resistance. Suppressor of cytokine signaling (SOCS)-3 and protein-...

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Detalles Bibliográficos
Autores principales: Briancon, Nadege, McNay, David E., Maratos-Flier, Eleftheria, Flier, Jeffrey S.
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2010
Materias:
Obesity Studies
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2992768/
https://www.ncbi.nlm.nih.gov/pubmed/20876718
http://dx.doi.org/10.2337/db10-0481

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