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Candesartan Attenuates Diabetic Retinal Vascular Pathology by Restoring Glyoxalase-I Function

OBJECTIVE: Advanced glycation end products (AGEs) and the renin-angiotensin system (RAS) are both implicated in the development of diabetic retinopathy. How these pathways interact to promote retinal vasculopathy is not fully understood. Glyoxalase-I (GLO-I) is an enzyme critical for the detoxificat...

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Detalles Bibliográficos
Autores principales:	Miller, Antonia G., Tan, Genevieve, Binger, Katrina J., Pickering, Raelene J., Thomas, Merlin C., Nagaraj, Ram H., Cooper, Mark E., Wilkinson-Berka, Jennifer L.
Formato:	Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2010
Materias:	Complications
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2992784/ https://www.ncbi.nlm.nih.gov/pubmed/20852029 http://dx.doi.org/10.2337/db10-0552

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