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Evolution of the HIV-1 nef gene in HLA-B*57 Positive Elite Suppressors

Elite controllers or suppressors (ES) are HIV-1 infected patients who maintain viral loads of < 50 copies/ml without antiretroviral therapy. CD8+ T cells are thought to play a key role in the control of viral replication and exert selective pressure on gag and nef in HLA-B*57 positive ES. We prev...

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Detalles Bibliográficos
Autores principales: Salgado, Maria, Brennan, Timothy P, O'Connell, Karen A, Bailey, Justin R, Ray, Stuart C, Siliciano, Robert F, Blankson, Joel N
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2993647/
https://www.ncbi.nlm.nih.gov/pubmed/21059238
http://dx.doi.org/10.1186/1742-4690-7-94