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Evolution of the HIV-1 nef gene in HLA-B*57 Positive Elite Suppressors
Elite controllers or suppressors (ES) are HIV-1 infected patients who maintain viral loads of < 50 copies/ml without antiretroviral therapy. CD8+ T cells are thought to play a key role in the control of viral replication and exert selective pressure on gag and nef in HLA-B*57 positive ES. We prev...
Autores principales: | Salgado, Maria, Brennan, Timothy P, O'Connell, Karen A, Bailey, Justin R, Ray, Stuart C, Siliciano, Robert F, Blankson, Joel N |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2993647/ https://www.ncbi.nlm.nih.gov/pubmed/21059238 http://dx.doi.org/10.1186/1742-4690-7-94 |
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