Cargando…
DNA double-strand break signaling and human disorders
DNA double-strand breaks are among the most serious types of DNA damage and their signaling and repair is critical for all cells and organisms. The repair of both induced and programmed DNA breaks is fundamental as demonstrated by the many human syndromes, neurodegenerative diseases, immunodeficienc...
Autores principales: | Bohgaki, Toshiyuki, Bohgaki, Miyuki, Hakem, Razqallah |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2993650/ https://www.ncbi.nlm.nih.gov/pubmed/21054854 http://dx.doi.org/10.1186/2041-9414-1-15 |
Ejemplares similares
-
Caspase-8 inactivation in T cells increases necroptosis and suppresses autoimmunity in Bim(−/−) mice
por: Bohgaki, Toshiyuki, et al.
Publicado: (2011) -
Genomic Instability, Defective Spermatogenesis, Immunodeficiency, and Cancer in a Mouse Model of the RIDDLE Syndrome
por: Bohgaki, Toshiyuki, et al.
Publicado: (2011) -
RNF168 and USP10 regulate topoisomerase IIα function via opposing effects on its ubiquitylation
por: Guturi, Kiran Kumar Naidu, et al.
Publicado: (2016) -
Inactivation of Chk2 and Mus81 Leads to Impaired Lymphocytes Development, Reduced Genomic Instability, and Suppression of Cancer
por: El Ghamrasni, Samah, et al.
Publicado: (2011) -
Successful treatment with clarithromycin for patients with polymyalgia rheumatica
por: Ohe, Masashi, et al.
Publicado: (2014)