COX-2 activation is associated with Akt phosphorylation and poor survival in ER-negative, HER2-positive breast cancer

BACKGROUND: Inducible cyclooxgenase-2 (COX-2) is commonly overexpressed in breast tumors and is a target for cancer therapy. Here, we studied the association of COX-2 with breast cancer survival and how this association is influenced by tumor estrogen and HER2 receptor status and Akt pathway activat...

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Detalles Bibliográficos
Autores principales: Glynn, Sharon A, Prueitt, Robyn L, Ridnour, Lisa A, Boersma, Brenda J, Dorsey, Tiffany M, Wink, David A, Goodman, Julie E, Yfantis, Harris G, Lee, Dong H, Ambs, Stefan
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2993681/
https://www.ncbi.nlm.nih.gov/pubmed/21078168
http://dx.doi.org/10.1186/1471-2407-10-626

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2993681/
https://www.ncbi.nlm.nih.gov/pubmed/21078168
http://dx.doi.org/10.1186/1471-2407-10-626

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