An unusual complication of polyarteritis nodosa with massive retroperitoneal hemorrhage: a case report

BACKGROUND AND CASE REPORT: Polyarteritis Nodosa (PAN) is a systemic necrotizing vasculitis that affects medium-sized and occasionally involves small arteries leading to the disruption of the internal and external elastic lamina and contribute to the development of aneurysms. Aneurysms develop at bi...

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Autores principales: Peddi, Prashanth, Kalavakunta, Jagadeesh K, Annakula, Madhavi, Armstrong, John R
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2993688/
https://www.ncbi.nlm.nih.gov/pubmed/21070670
http://dx.doi.org/10.1186/1755-7682-3-31
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author Peddi, Prashanth
Kalavakunta, Jagadeesh K
Annakula, Madhavi
Armstrong, John R
author_facet Peddi, Prashanth
Kalavakunta, Jagadeesh K
Annakula, Madhavi
Armstrong, John R
author_sort Peddi, Prashanth
collection PubMed
description BACKGROUND AND CASE REPORT: Polyarteritis Nodosa (PAN) is a systemic necrotizing vasculitis that affects medium-sized and occasionally involves small arteries leading to the disruption of the internal and external elastic lamina and contribute to the development of aneurysms. Aneurysms develop at bifurcation of major blood vessels; they are prone to thrombosis, rupture and haemorrhage. Retroperitoneal haemorrhage around kidneys was previously reported in patients with PAN. We report a case of massive retroperitoneal bleeding from inferior pancreaticoduodenal artery aneurysm rupture in a 70-year-old female with PAN. CONCLUSION: Prognosis of untreated PAN is very poor with 20% 5 year survival rate, therefore early recognition of the disease will prevent catastrophic complications and improves survival.
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spelling pubmed-29936882010-11-30 An unusual complication of polyarteritis nodosa with massive retroperitoneal hemorrhage: a case report Peddi, Prashanth Kalavakunta, Jagadeesh K Annakula, Madhavi Armstrong, John R Int Arch Med Case Report BACKGROUND AND CASE REPORT: Polyarteritis Nodosa (PAN) is a systemic necrotizing vasculitis that affects medium-sized and occasionally involves small arteries leading to the disruption of the internal and external elastic lamina and contribute to the development of aneurysms. Aneurysms develop at bifurcation of major blood vessels; they are prone to thrombosis, rupture and haemorrhage. Retroperitoneal haemorrhage around kidneys was previously reported in patients with PAN. We report a case of massive retroperitoneal bleeding from inferior pancreaticoduodenal artery aneurysm rupture in a 70-year-old female with PAN. CONCLUSION: Prognosis of untreated PAN is very poor with 20% 5 year survival rate, therefore early recognition of the disease will prevent catastrophic complications and improves survival. BioMed Central 2010-11-11 /pmc/articles/PMC2993688/ /pubmed/21070670 http://dx.doi.org/10.1186/1755-7682-3-31 Text en Copyright ©2010 Peddi et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Peddi, Prashanth
Kalavakunta, Jagadeesh K
Annakula, Madhavi
Armstrong, John R
An unusual complication of polyarteritis nodosa with massive retroperitoneal hemorrhage: a case report
title An unusual complication of polyarteritis nodosa with massive retroperitoneal hemorrhage: a case report
title_full An unusual complication of polyarteritis nodosa with massive retroperitoneal hemorrhage: a case report
title_fullStr An unusual complication of polyarteritis nodosa with massive retroperitoneal hemorrhage: a case report
title_full_unstemmed An unusual complication of polyarteritis nodosa with massive retroperitoneal hemorrhage: a case report
title_short An unusual complication of polyarteritis nodosa with massive retroperitoneal hemorrhage: a case report
title_sort unusual complication of polyarteritis nodosa with massive retroperitoneal hemorrhage: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2993688/
https://www.ncbi.nlm.nih.gov/pubmed/21070670
http://dx.doi.org/10.1186/1755-7682-3-31
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