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C-jun Inhibits Mammary Apoptosis In Vivo
c-jun, which is overexpressed in a number of human cancers encodes a critical component of the AP-1 complex. c-jun has been shown to either induce or inhibit cellular apoptosis. Germ line deletion of both c-jun alleles is embryonically lethal. To determine the role of the endogenous c-jun gene in ap...
Autores principales: | Katiyar, Sanjay, Casimiro, Mathew C., Dettin, Luis, Ju, Xiaoming, Wagner, Erwin F., Tanaka, Hirokazu, Pestell, Richard G. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2993753/ https://www.ncbi.nlm.nih.gov/pubmed/20926681 http://dx.doi.org/10.1091/mbc.E10-08-0705 |
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