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P53 levels govern the choice between senescence and quiescence
The mechanism(s) by which p53 chooses between outcomes of senescence or quiescence has remained elusive. A paper published in the recent issue of Cell Cycle indicates that this decision may be determined by p53 levels and their ability to selectively down-regulate mTOR signaling.
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Impact Journals LLC
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2993792/ |
| _version_ | 1782192846655193088 |
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| author | Meek, David W. |
| author_facet | Meek, David W. |
| author_sort | Meek, David W. |
| collection | PubMed |
| description | The mechanism(s) by which p53 chooses between outcomes of senescence or quiescence has remained elusive. A paper published in the recent issue of Cell Cycle indicates that this decision may be determined by p53 levels and their ability to selectively down-regulate mTOR signaling. |
| format | Text |
| id | pubmed-2993792 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2010 |
| publisher | Impact Journals LLC |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-29937922010-11-30 P53 levels govern the choice between senescence and quiescence Meek, David W. Aging (Albany NY) Editorial The mechanism(s) by which p53 chooses between outcomes of senescence or quiescence has remained elusive. A paper published in the recent issue of Cell Cycle indicates that this decision may be determined by p53 levels and their ability to selectively down-regulate mTOR signaling. Impact Journals LLC 2010-10-20 /pmc/articles/PMC2993792/ Text en Copyright: © 2010 Meek |
| spellingShingle | Editorial Meek, David W. P53 levels govern the choice between senescence and quiescence |
| title | P53 levels govern the choice between senescence and quiescence |
| title_full | P53 levels govern the choice between senescence and quiescence |
| title_fullStr | P53 levels govern the choice between senescence and quiescence |
| title_full_unstemmed | P53 levels govern the choice between senescence and quiescence |
| title_short | P53 levels govern the choice between senescence and quiescence |
| title_sort | p53 levels govern the choice between senescence and quiescence |
| topic | Editorial |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2993792/ |
| work_keys_str_mv | AT meekdavidw p53levelsgovernthechoicebetweensenescenceandquiescence |