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P53 levels govern the choice between senescence and quiescence
The mechanism(s) by which p53 chooses between outcomes of senescence or quiescence has remained elusive. A paper published in the recent issue of Cell Cycle indicates that this decision may be determined by p53 levels and their ability to selectively down-regulate mTOR signaling.
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| Formato: | Texto |
| Lenguaje: | English |
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Impact Journals LLC
2010
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2993792/ |