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Telomere sister chromatid exchange and the process of aging

Telomeres are a hotspot for sister chromatid exchange (T-SCE). Any biological consequence of this form of instability remained obscure until quantitative modeling revealed a link between elevated T-SCE rates and accelerated cellular replicative senescence. This work strongly suggests that progressiv...

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Detalles Bibliográficos
Autores principales:	Blagoev, Krastan B., Goodwin, Edwin H., Bailey, Susan M.
Formato:	Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2010
Materias:	Research Perspective
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2993801/ https://www.ncbi.nlm.nih.gov/pubmed/20952810

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