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Intranasal Immunization with Influenza VLPs Incorporating Membrane-Anchored Flagellin Induces Strong Heterosubtypic Protection

We demonstrated previously that the incorporation of a membrane-anchored form of flagellin into influenza virus-like particles (VLPs) improved the immunogenicity of VLPs significantly, inducing partially protective heterosubtypic immunity by intramuscular immunization. Because the efficacy of mucosa...

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Detalles Bibliográficos
Autores principales:	Wang, Bao-Zhong, Xu, Rui, Quan, Fu-Shi, Kang, Sang-Moo, Wang, Li, Compans, Richard W.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2993933/ https://www.ncbi.nlm.nih.gov/pubmed/21124769 http://dx.doi.org/10.1371/journal.pone.0013972

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