Synaptic Protection in the Brain of Wld(S) Mice Occurs Independently of Age but Is Sensitive to Gene-Dose

BACKGROUND: Disruption of synaptic connectivity is a significant early event in many neurodegenerative conditions affecting the aging CNS, including Alzheimer's disease and Parkinson's disease. Therapeutic approaches that protect synapses from degeneration in the aging brain offer the pote...

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Detalles Bibliográficos
Autores principales: Wright, Ann K., Wishart, Thomas M., Ingham, Cali A., Gillingwater, Thomas H.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2993971/
https://www.ncbi.nlm.nih.gov/pubmed/21124744
http://dx.doi.org/10.1371/journal.pone.0015108

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2993971/
https://www.ncbi.nlm.nih.gov/pubmed/21124744
http://dx.doi.org/10.1371/journal.pone.0015108

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