The Formulated Microbicide RC-101 Was Safe and Antivirally Active Following Intravaginal Application in Pigtailed Macaques

BACKGROUND: RC-101 is a congener of the antiretroviral peptide retrocyclin, which we and others have reported is active against clinical HIV-1 isolates from all major clades, does not hemagglutinate, and is non-toxic and non-inflammatory in cervicovaginal cell culture. Herein, film-formulated RC-101...

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Detalles Bibliográficos
Autores principales: Cole, Alexander M., Patton, Dorothy L., Rohan, Lisa C., Cole, Amy L., Cosgrove-Sweeney, Yvonne, Rogers, Nicole A., Ratner, Deena, Sassi, Alexandra B., Lackman-Smith, Carol, Tarwater, Patrick, Ramratnam, Bharat, Ruchala, Piotr, Lehrer, Robert I., Waring, Alan J., Gupta, Phalguni
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2993972/
https://www.ncbi.nlm.nih.gov/pubmed/21124745
http://dx.doi.org/10.1371/journal.pone.0015111

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