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TRAIL-expressing mesenchymal stem cells kill the putative cancer stem cell population

BACKGROUND: Tumours contain stem-like, side population (SP) cells, which have increased tumorigenic potential, resistance to traditional therapies and may be responsible for treatment failures and relapse in patients. METHODS: Mesenchymal stem cells (MSCs) were engineered to express the apoptotic li...

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Detalles Bibliográficos
Autores principales:	Loebinger, M R, Sage, E K, Davies, D, Janes, S M
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2010
Materias:	Translational Therapeutics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2994223/ https://www.ncbi.nlm.nih.gov/pubmed/21063402 http://dx.doi.org/10.1038/sj.bjc.6605952

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