Maternal vitamin and iron supplementation and risk of infant leukaemia: a report from the Children's Oncology Group

BACKGROUND: Prenatal supplementation has been inversely associated with childhood, but not with infant, leukaemia. METHODS: Mothers of 443 cases of infant leukaemia diagnosed during 1996–2006 and 324 frequency-matched controls completed interviews. Associations were evaluated by unconditional logist...

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Autores principales: Linabery, A M, Puumala, S E, Hilden, J M, Davies, S M, Heerema, N A, Roesler, M A, Ross, J A
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2010
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2994226/
https://www.ncbi.nlm.nih.gov/pubmed/20978510
http://dx.doi.org/10.1038/sj.bjc.6605957
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author Linabery, A M
Puumala, S E
Hilden, J M
Davies, S M
Heerema, N A
Roesler, M A
Ross, J A
author_facet Linabery, A M
Puumala, S E
Hilden, J M
Davies, S M
Heerema, N A
Roesler, M A
Ross, J A
author_sort Linabery, A M
collection PubMed
description BACKGROUND: Prenatal supplementation has been inversely associated with childhood, but not with infant, leukaemia. METHODS: Mothers of 443 cases of infant leukaemia diagnosed during 1996–2006 and 324 frequency-matched controls completed interviews. Associations were evaluated by unconditional logistic regression. RESULTS: We observed no associations between prenatal vitamin (odds ratio (OR)=0.79, 95% confidence interval (CI): 0.44–1.42) or iron supplementation (OR=1.07, 95% CI: 0.75–1.52) and infant leukaemia after adjustment for race/ethnicity and income. Similar results were observed for leukaemia subtypes analysed separately. CONCLUSION: The observed null associations may be attributable to high supplementation rates and/or national fortification programmes.
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spelling pubmed-29942262011-11-01 Maternal vitamin and iron supplementation and risk of infant leukaemia: a report from the Children's Oncology Group Linabery, A M Puumala, S E Hilden, J M Davies, S M Heerema, N A Roesler, M A Ross, J A Br J Cancer Short Communication BACKGROUND: Prenatal supplementation has been inversely associated with childhood, but not with infant, leukaemia. METHODS: Mothers of 443 cases of infant leukaemia diagnosed during 1996–2006 and 324 frequency-matched controls completed interviews. Associations were evaluated by unconditional logistic regression. RESULTS: We observed no associations between prenatal vitamin (odds ratio (OR)=0.79, 95% confidence interval (CI): 0.44–1.42) or iron supplementation (OR=1.07, 95% CI: 0.75–1.52) and infant leukaemia after adjustment for race/ethnicity and income. Similar results were observed for leukaemia subtypes analysed separately. CONCLUSION: The observed null associations may be attributable to high supplementation rates and/or national fortification programmes. Nature Publishing Group 2010-11 2010-10-26 /pmc/articles/PMC2994226/ /pubmed/20978510 http://dx.doi.org/10.1038/sj.bjc.6605957 Text en Copyright © 2010 Cancer Research UK https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material.If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Short Communication
Linabery, A M
Puumala, S E
Hilden, J M
Davies, S M
Heerema, N A
Roesler, M A
Ross, J A
Maternal vitamin and iron supplementation and risk of infant leukaemia: a report from the Children's Oncology Group
title Maternal vitamin and iron supplementation and risk of infant leukaemia: a report from the Children's Oncology Group
title_full Maternal vitamin and iron supplementation and risk of infant leukaemia: a report from the Children's Oncology Group
title_fullStr Maternal vitamin and iron supplementation and risk of infant leukaemia: a report from the Children's Oncology Group
title_full_unstemmed Maternal vitamin and iron supplementation and risk of infant leukaemia: a report from the Children's Oncology Group
title_short Maternal vitamin and iron supplementation and risk of infant leukaemia: a report from the Children's Oncology Group
title_sort maternal vitamin and iron supplementation and risk of infant leukaemia: a report from the children's oncology group
topic Short Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2994226/
https://www.ncbi.nlm.nih.gov/pubmed/20978510
http://dx.doi.org/10.1038/sj.bjc.6605957
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