Cargando…
Saloplastic Macroporous Polyelectrolyte Complexes: Cartilage Mimics
[Image: see text] Complexes of sodium poly(4-styrenesulfonate) (NaPSS) and poly(diallyldimethylammonium chloride) (PDADMAC) were formed on mixing equimolar solutions in high salt concentration. Under ultracentrifugal fields, the complex precipitates were transformed into compact polyelectrolyte comp...
Autores principales: | , |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2010
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2994323/ https://www.ncbi.nlm.nih.gov/pubmed/21132107 http://dx.doi.org/10.1021/ma1012978 |
_version_ | 1782192915789905920 |
---|---|
author | Hariri, Haifa H. Schlenoff, Joseph B. |
author_facet | Hariri, Haifa H. Schlenoff, Joseph B. |
author_sort | Hariri, Haifa H. |
collection | PubMed |
description | [Image: see text] Complexes of sodium poly(4-styrenesulfonate) (NaPSS) and poly(diallyldimethylammonium chloride) (PDADMAC) were formed on mixing equimolar solutions in high salt concentration. Under ultracentrifugal fields, the complex precipitates were transformed into compact polyelectrolyte complexes (CoPECs), which showed extensive porosity. The mechanical properties of CoPECS make them attractive for bioimplants and tissue engineering applications. Free NaPSS chains in the closed pores of CoPECs create excess osmotic pressure, which controls the pore size and contributes to the mechanical resistance of the material. The mechanical properties of CoPECs, modulated by the ionic strength of the doping medium, were studied by uniaxial tensile testing and the stress−strain data were fit to a three-element Maxwell model which revealed at least two regimes of stress relaxation. |
format | Text |
id | pubmed-2994323 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2010 |
publisher | American Chemical Society |
record_format | MEDLINE/PubMed |
spelling | pubmed-29943232011-10-26 Saloplastic Macroporous Polyelectrolyte Complexes: Cartilage Mimics Hariri, Haifa H. Schlenoff, Joseph B. Macromolecules [Image: see text] Complexes of sodium poly(4-styrenesulfonate) (NaPSS) and poly(diallyldimethylammonium chloride) (PDADMAC) were formed on mixing equimolar solutions in high salt concentration. Under ultracentrifugal fields, the complex precipitates were transformed into compact polyelectrolyte complexes (CoPECs), which showed extensive porosity. The mechanical properties of CoPECS make them attractive for bioimplants and tissue engineering applications. Free NaPSS chains in the closed pores of CoPECs create excess osmotic pressure, which controls the pore size and contributes to the mechanical resistance of the material. The mechanical properties of CoPECs, modulated by the ionic strength of the doping medium, were studied by uniaxial tensile testing and the stress−strain data were fit to a three-element Maxwell model which revealed at least two regimes of stress relaxation. American Chemical Society 2010-09-22 2010-10-26 /pmc/articles/PMC2994323/ /pubmed/21132107 http://dx.doi.org/10.1021/ma1012978 Text en Copyright © 2010 American Chemical Society This is an open access article published under an ACS AuthorChoice License (http://pubs.acs.org/page/policy/authorchoice_termsofuse.html) , which permits copying and redistribution of the article or any adaptations for non-commercial purposes. |
spellingShingle | Hariri, Haifa H. Schlenoff, Joseph B. Saloplastic Macroporous Polyelectrolyte Complexes: Cartilage Mimics |
title | Saloplastic Macroporous Polyelectrolyte Complexes: Cartilage Mimics |
title_full | Saloplastic Macroporous Polyelectrolyte Complexes: Cartilage Mimics |
title_fullStr | Saloplastic Macroporous Polyelectrolyte Complexes: Cartilage Mimics |
title_full_unstemmed | Saloplastic Macroporous Polyelectrolyte Complexes: Cartilage Mimics |
title_short | Saloplastic Macroporous Polyelectrolyte Complexes: Cartilage Mimics |
title_sort | saloplastic macroporous polyelectrolyte complexes: cartilage mimics |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2994323/ https://www.ncbi.nlm.nih.gov/pubmed/21132107 http://dx.doi.org/10.1021/ma1012978 |
work_keys_str_mv | AT haririhaifah saloplasticmacroporouspolyelectrolytecomplexescartilagemimics AT schlenoffjosephb saloplasticmacroporouspolyelectrolytecomplexescartilagemimics |