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Ocular infection of mice with an avirulent recombinant HSV-1 expressing IL-4 and an attenuated HSV-1 strain generates virulent recombinants in vivo

PURPOSE: To assess the relative impact of overexpression of interleukin 2 (IL-2), interleukin 4 (IL-4), and interferon gamma (IFN-γ) expressing recombinant herpes simplex virus type 1 (HSV-1) on altering immune responses in ocularly infected mice. METHODS: BALB/c mice were co-infected ocularly with...

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Detalles Bibliográficos
Autores principales:	Mott, Kevin R., Wechsler, Steven L., Ghiasi, Homayon
Formato:	Texto
Lenguaje:	English
Publicado:	Molecular Vision 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2994333/ https://www.ncbi.nlm.nih.gov/pubmed/21139679

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