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Bevacizumab therapy normalizes the pathological intraocular environment beyond neutralizing VEGF

PURPOSE: Vascular endothelial growth factor (VEGF) plays a key role in neovascularization by stimulating the proliferation and migration of vascular endothelial cells. The anti-VEGF therapy bevacizumab acts by binding to VEGF and preventing its effects. However, this linear interaction represents on...

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Detalles Bibliográficos
Autores principales: Sharma, Rajesh K., Rogojina, Anna T., Chalam, K.V.
Formato: Texto
Lenguaje:English
Publicado: Molecular Vision 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2994336/
https://www.ncbi.nlm.nih.gov/pubmed/21139682