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The effect of phosphorylated Akt inhibition on posterior capsule opacification in an ex vivo canine model

PURPOSE: To evaluate whether inhibition of phosphorylated Akt (pAkt) would reduce or prevent posterior capsule opacification (PCO) in an ex vivo canine lens capsule model. METHODS: Normal and cataractous lenses (n=6) were evaluated for pAkt via immunohistochemistry and immunoblotting. Primary cultur...

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Detalles Bibliográficos
Autores principales: Chandler, Heather L., Webb, Terah R., Barden, Curtis A., Thangavelu, Mirunalni, Kulp, Samuel K., Chen, Ching-Shih, Colitz, Carmen M.H.
Formato: Texto
Lenguaje:English
Publicado: Molecular Vision 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2994344/
https://www.ncbi.nlm.nih.gov/pubmed/21139685