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Sclerosing angiomatoid nodular transformation of the spleen masquerading as a sarcoma metastasis
We report a case of sclerosing angiomatoid nodular transformation (SANT) of the spleen presenting as an incidental splenic mass in a patient with a history of retroperitoneal spindle cell sarcoma. Imaging studies and preoperative fine needle biopsy failed to differentiate this lesion from other vasc...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
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PagePress
2010
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2994526/ https://www.ncbi.nlm.nih.gov/pubmed/21139961 http://dx.doi.org/10.4081/rt.2010.e46 |
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author | Sitaraman, Lalitha M Linn, John G Matkowskyj, Kristina A Wayne, Jeffrey D |
author_facet | Sitaraman, Lalitha M Linn, John G Matkowskyj, Kristina A Wayne, Jeffrey D |
author_sort | Sitaraman, Lalitha M |
collection | PubMed |
description | We report a case of sclerosing angiomatoid nodular transformation (SANT) of the spleen presenting as an incidental splenic mass in a patient with a history of retroperitoneal spindle cell sarcoma. Imaging studies and preoperative fine needle biopsy failed to differentiate this lesion from other vascular splenic lesions or a metastatic focus of a prior sarcoma. The patient was treated with splenectomy, which has proved both diagnostic and therapeutic in this and other cases of SANT. Although histology can lead to the diagnosis of vascular tumor, immunohistochemistry is the only way to confirm the diagnosis of SANT. The etiology of SANT is unknown. SANT of the spleen is a benign lesion that does not recur after splenectomy. |
format | Text |
id | pubmed-2994526 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2010 |
publisher | PagePress |
record_format | MEDLINE/PubMed |
spelling | pubmed-29945262010-12-07 Sclerosing angiomatoid nodular transformation of the spleen masquerading as a sarcoma metastasis Sitaraman, Lalitha M Linn, John G Matkowskyj, Kristina A Wayne, Jeffrey D Rare Tumors Case Report We report a case of sclerosing angiomatoid nodular transformation (SANT) of the spleen presenting as an incidental splenic mass in a patient with a history of retroperitoneal spindle cell sarcoma. Imaging studies and preoperative fine needle biopsy failed to differentiate this lesion from other vascular splenic lesions or a metastatic focus of a prior sarcoma. The patient was treated with splenectomy, which has proved both diagnostic and therapeutic in this and other cases of SANT. Although histology can lead to the diagnosis of vascular tumor, immunohistochemistry is the only way to confirm the diagnosis of SANT. The etiology of SANT is unknown. SANT of the spleen is a benign lesion that does not recur after splenectomy. PagePress 2010-09-30 /pmc/articles/PMC2994526/ /pubmed/21139961 http://dx.doi.org/10.4081/rt.2010.e46 Text en ©Copyright L.M. Sitaraman et al., 2010 This work is licensed under a Creative Commons Attribution 3.0 License (by-nc 3.0). Licensee PAGEPress, Italy |
spellingShingle | Case Report Sitaraman, Lalitha M Linn, John G Matkowskyj, Kristina A Wayne, Jeffrey D Sclerosing angiomatoid nodular transformation of the spleen masquerading as a sarcoma metastasis |
title | Sclerosing angiomatoid nodular transformation of the spleen masquerading as a sarcoma metastasis |
title_full | Sclerosing angiomatoid nodular transformation of the spleen masquerading as a sarcoma metastasis |
title_fullStr | Sclerosing angiomatoid nodular transformation of the spleen masquerading as a sarcoma metastasis |
title_full_unstemmed | Sclerosing angiomatoid nodular transformation of the spleen masquerading as a sarcoma metastasis |
title_short | Sclerosing angiomatoid nodular transformation of the spleen masquerading as a sarcoma metastasis |
title_sort | sclerosing angiomatoid nodular transformation of the spleen masquerading as a sarcoma metastasis |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2994526/ https://www.ncbi.nlm.nih.gov/pubmed/21139961 http://dx.doi.org/10.4081/rt.2010.e46 |
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