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Sclerosing angiomatoid nodular transformation of the spleen masquerading as a sarcoma metastasis

We report a case of sclerosing angiomatoid nodular transformation (SANT) of the spleen presenting as an incidental splenic mass in a patient with a history of retroperitoneal spindle cell sarcoma. Imaging studies and preoperative fine needle biopsy failed to differentiate this lesion from other vasc...

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Autores principales: Sitaraman, Lalitha M, Linn, John G, Matkowskyj, Kristina A, Wayne, Jeffrey D
Formato: Texto
Lenguaje:English
Publicado: PagePress 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2994526/
https://www.ncbi.nlm.nih.gov/pubmed/21139961
http://dx.doi.org/10.4081/rt.2010.e46
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author Sitaraman, Lalitha M
Linn, John G
Matkowskyj, Kristina A
Wayne, Jeffrey D
author_facet Sitaraman, Lalitha M
Linn, John G
Matkowskyj, Kristina A
Wayne, Jeffrey D
author_sort Sitaraman, Lalitha M
collection PubMed
description We report a case of sclerosing angiomatoid nodular transformation (SANT) of the spleen presenting as an incidental splenic mass in a patient with a history of retroperitoneal spindle cell sarcoma. Imaging studies and preoperative fine needle biopsy failed to differentiate this lesion from other vascular splenic lesions or a metastatic focus of a prior sarcoma. The patient was treated with splenectomy, which has proved both diagnostic and therapeutic in this and other cases of SANT. Although histology can lead to the diagnosis of vascular tumor, immunohistochemistry is the only way to confirm the diagnosis of SANT. The etiology of SANT is unknown. SANT of the spleen is a benign lesion that does not recur after splenectomy.
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spelling pubmed-29945262010-12-07 Sclerosing angiomatoid nodular transformation of the spleen masquerading as a sarcoma metastasis Sitaraman, Lalitha M Linn, John G Matkowskyj, Kristina A Wayne, Jeffrey D Rare Tumors Case Report We report a case of sclerosing angiomatoid nodular transformation (SANT) of the spleen presenting as an incidental splenic mass in a patient with a history of retroperitoneal spindle cell sarcoma. Imaging studies and preoperative fine needle biopsy failed to differentiate this lesion from other vascular splenic lesions or a metastatic focus of a prior sarcoma. The patient was treated with splenectomy, which has proved both diagnostic and therapeutic in this and other cases of SANT. Although histology can lead to the diagnosis of vascular tumor, immunohistochemistry is the only way to confirm the diagnosis of SANT. The etiology of SANT is unknown. SANT of the spleen is a benign lesion that does not recur after splenectomy. PagePress 2010-09-30 /pmc/articles/PMC2994526/ /pubmed/21139961 http://dx.doi.org/10.4081/rt.2010.e46 Text en ©Copyright L.M. Sitaraman et al., 2010 This work is licensed under a Creative Commons Attribution 3.0 License (by-nc 3.0). Licensee PAGEPress, Italy
spellingShingle Case Report
Sitaraman, Lalitha M
Linn, John G
Matkowskyj, Kristina A
Wayne, Jeffrey D
Sclerosing angiomatoid nodular transformation of the spleen masquerading as a sarcoma metastasis
title Sclerosing angiomatoid nodular transformation of the spleen masquerading as a sarcoma metastasis
title_full Sclerosing angiomatoid nodular transformation of the spleen masquerading as a sarcoma metastasis
title_fullStr Sclerosing angiomatoid nodular transformation of the spleen masquerading as a sarcoma metastasis
title_full_unstemmed Sclerosing angiomatoid nodular transformation of the spleen masquerading as a sarcoma metastasis
title_short Sclerosing angiomatoid nodular transformation of the spleen masquerading as a sarcoma metastasis
title_sort sclerosing angiomatoid nodular transformation of the spleen masquerading as a sarcoma metastasis
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2994526/
https://www.ncbi.nlm.nih.gov/pubmed/21139961
http://dx.doi.org/10.4081/rt.2010.e46
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