Retrieval of the Alzheimer's amyloid precursor protein from the endosome to the TGN is S655 phosphorylation state-dependent and retromer-mediated

BACKGROUND: Retrograde transport of several transmembrane proteins from endosomes to the trans-Golgi network (TGN) occurs via Rab 5-containing endosomes, mediated by clathrin and the recently characterized retromer complex. This complex and one of its putative sorting receptor components, SorLA, wer...

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Detalles Bibliográficos
Autores principales: Vieira, Sandra I, Rebelo, Sandra, Esselmann, Hermann, Wiltfang, Jens, Lah, James, Lane, Rachel, Small, Scott A, Gandy, Sam, da Cruz e Silva, Edgar F, da Cruz e Silva, Odete AB
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2994555/
https://www.ncbi.nlm.nih.gov/pubmed/20937087
http://dx.doi.org/10.1186/1750-1326-5-40

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