Homodimerization of the Death-Associated Protein Kinase Catalytic Domain: Development of a New Small Molecule Fluorescent Reporter

BACKGROUND: Death-Associated Protein Kinase (DAPK) is a member of the Ca(2+)/calmodulin regulated serine/threonine protein kinases. Its biological function has been associated with induced cell death, and in vivo use of selective small molecule inhibitors of DAPK catalytic activity has demonstrated...

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Detalles Bibliográficos
Autores principales: Zimmermann, Michael, Atmanene, Cédric, Xu, Qingyan, Fouillen, Laetitia, Van Dorsselaer, Alain, Bonnet, Dominique, Marsol, Claire, Hibert, Marcel, Sanglier-Cianferani, Sarah, Pigault, Claire, McNamara, Laurie K., Watterson, D. Martin, Haiech, Jacques, Kilhoffer, Marie-Claude
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2994711/
https://www.ncbi.nlm.nih.gov/pubmed/21152427
http://dx.doi.org/10.1371/journal.pone.0014120

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