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Biased Signaling of the Angiotensin II Type 1 Receptor Can Be Mediated through Distinct Mechanisms

BACKGROUND: Seven transmembrane receptors (7TMRs) can adopt different active conformations facilitating a selective activation of either G protein or β-arrestin-dependent signaling pathways. This represents an opportunity for development of novel therapeutics targeting selective biological effects o...

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Detalles Bibliográficos
Autores principales:	Bonde, Marie Mi, Hansen, Jonas Tind, Sanni, Samra Joke, Haunsø, Stig, Gammeltoft, Steen, Lyngsø, Christina, Hansen, Jakob Lerche
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2994726/ https://www.ncbi.nlm.nih.gov/pubmed/21152433 http://dx.doi.org/10.1371/journal.pone.0014135

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