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Administration of pigment epithelium-derived factor delivered by adeno-associated virus inhibits blood–retinal barrier breakdown in diabetic rats

PURPOSE: To evaluate the effect of the recombinant adeno-associated virus (rAAV) vector that expresses human pigment epithelium-derived factor (hPEDF) on reducing blood–retinal barrier (BRB) breakdown in the experimental diabetic rat model. METHODS: Diabetes was induced by an intraperitoneal (i.p.)...

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Detalles Bibliográficos
Autores principales:	Yu, Hai, Chen, Lei, Jiang, Jing
Formato:	Texto
Lenguaje:	English
Publicado:	Molecular Vision 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2994733/ https://www.ncbi.nlm.nih.gov/pubmed/21139695

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