Cargando…

The MRX Complex Plays Multiple Functions in Resection of Yku- and Rif2-Protected DNA Ends

The ends of both double-strand breaks (DSBs) and telomeres undergo tightly regulated 5′ to 3′ resection. Resection of DNA ends, which is specifically inhibited during the G1 cell cycle phase, requires the MRX complex, Sae2, Sgs1 and Exo1. Moreover, it is negatively regulated by the non-homologous en...

Descripción completa

Detalles Bibliográficos
Autores principales: Bonetti, Diego, Clerici, Michela, Manfrini, Nicola, Lucchini, Giovanna, Longhese, Maria Pia
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2994746/
https://www.ncbi.nlm.nih.gov/pubmed/21152442
http://dx.doi.org/10.1371/journal.pone.0014142