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IGF-IR Internalizes with Caveolin-1 and PTRF/Cavin in Hacat Cells
BACKGROUND: Insulin-like growth factor-I receptor (IGF-IR) is a tyrosine kinase receptor (RTK) associated with caveolae, invaginations of the plasma membrane that regulate vesicular transport, endocytosis and intracellular signaling. IGF-IR internalization represents a key mechanism of down-modulati...
Autores principales: | , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2994771/ https://www.ncbi.nlm.nih.gov/pubmed/21152401 http://dx.doi.org/10.1371/journal.pone.0014157 |