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IGF-IR Internalizes with Caveolin-1 and PTRF/Cavin in Hacat Cells

BACKGROUND: Insulin-like growth factor-I receptor (IGF-IR) is a tyrosine kinase receptor (RTK) associated with caveolae, invaginations of the plasma membrane that regulate vesicular transport, endocytosis and intracellular signaling. IGF-IR internalization represents a key mechanism of down-modulati...

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Detalles Bibliográficos
Autores principales: Salani, Barbara, Passalacqua, Mario, Maffioli, Sara, Briatore, Lucia, Hamoudane, Meriem, Contini, Paola, Cordera, Renzo, Maggi, Davide
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2994771/
https://www.ncbi.nlm.nih.gov/pubmed/21152401
http://dx.doi.org/10.1371/journal.pone.0014157